Contact Information
Detailed Information
Fosfomycin 3gm sachet is an antibiotic medication used to treat bacterial infections, particularly:
-
Urinary tract infections (UTIs)
-
Prostatitis (inflammation of the prostate)
-
Gastrointestinal infections
It works by inhibiting bacterial cell wall formation, ultimately leading to the death of the bacteria.
Key points:
-
Available in oral and injectable forms
-
Typically taken as a single dose for UTIs
-
Effective against a range of bacteria, including E. coli and Klebsiella
-
Generally well-tolerated, with few side effects.
Fosfomycin: Additional Points
-
Spectrum of activity: Fosfomycin is effective against a wide range of bacteria, including Gram-positive, Gram-negative, and anaerobic bacteria.
-
Mechanism of action: It inhibits the enzyme MurA, which is essential for bacterial cell wall synthesis.
-
Pharmacokinetics: Fosfomycin is rapidly absorbed after oral administration, with peak serum concentrations reached within 2 hours.
-
Half-life: The half-life of fosfomycin is approximately 5.7 hours.
-
Side effects: Common side effects include:
-
Gastrointestinal upset (nausea, diarrhea, abdominal pain)
-
Headache
-
Rash
-
Yeast infections (in women)
-
-
Contraindications: Fosfomycin is contraindicated in patients with:
-
Kidney disease (requires dose adjustment)
-
Severe hepatic impairment
-
-
Interactions: Fosfomycin may interact with:
-
Metoclopramide (increased absorption)
-
Antacids (decreased absorption)
-
-
Pregnancy and lactation: Fosfomycin is generally considered safe during pregnancy and lactation, but consult a healthcare professional before use.
Contact Fosfomycin (Monurol): Uses, Side Effects, Warnings & More